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科研队伍>>导师>>高明霞老师
  个人简历
 

2000年毕业于山东师范大学化学系,获得理学学士学位
2003年毕业于山东师范大学化学系,获得理学硕士学位
2006年毕业于复旦大学化学系, 获理学博士学位
2004年至今于复旦大学化学系从事教学和科学研究工作
2007年在德国的环境与健康国家研究中心(GSF-National Research Center for Environment and Health),从事复杂样品的分离和分析研究
2010年2月晋升副教授,硕士生导师
2017年晋升博士生导师
2018年晋升教授,同年在美国的圣母大学(University of Notre Dame)的Norman J. Dovichi教授课题组做访问学者,利用CE/MS技术研究爪蟾早期胚胎单个卵裂球表达的蛋白质分离分析。

 
教学经历

(1)主讲本科生基础课《分析化学II》,核心课程《生命中的化学元素》,博士生选修课《生物色谱》,参加硕士研究生实验课《高等仪器分析实验课》。参与《分析化学》课本的修订工作。
(2)培养硕士研究生8人,协助课题组老师培养博士生3人。近两年培养的研究生中获得国家奖学金4人次:王亚楠2次,王嘉希1次,张珮明1

 

高明霞(MingXia Gao) 教授 博士生导师

 

联系电话:021-65643983
E-MAIL:mxgao@fudan.edu.cn
联系地址:上海市淞沪路2005号复旦大学江湾校区化学楼4019室

 
研究方向   主要奖励和荣誉

色谱分析,蛋白质组学新技术新方法

肿瘤细胞捕获与高灵敏度成像检测

 

 

2016年复旦大学优秀共产党员
2010年度复旦大学十佳辅导员(研究生)
2011年The PSC Young Scientist Lecture Award
2009年十七届全国色谱会议优秀口头报告奖
2008年度复旦大学奖教金

研究成果   发表论文

发表署名文章38篇,其中本人作为通讯作者和第一作者文章26篇,其中有多篇发表在ACS Appl. Mater. InterfacesAnalytical Chemistry,等国际知名期刊


 

1. Jiaxi Wang, Jie Li, Mingxia Gao*, Xiangmin Zhang, Preparation of thickness-controlled Mg-MOFs based magnetic graphene composite as a novel hydrophilic matrix for the effective identification of glycopeptide in human urine. Nanoscale, 2019, 11, 3701 - 3709
2. Haoyang Zheng, Jiaxi Wang, Mingxia Gao*, Xiangmin Zhang, Titanium(IV)-functionalized zirconium-organic frameworks as dual-metal affinity probe for recognition of endogenous phosphopeptides prior to mass spectrometric quantification, Microchimica Acta, 2019, 186, 829
3. Jiaxi Wang, Jie Li, Mingxia Gao**, Xiangmin Zhang*, Recent advances in covalent organic frameworks for separation and analysis of complex samples, Trends in Analytical Chemistry, 2018, 108, 98-109
4. Meng Chen, Ling Zhang, Bo Yang, Mingxia Gao*, Xiangmin Zhang, Facile synthesis of terminal-alkyne bioorthogonal molecules for live -cell surface-enhanced Raman scattering imaging through Au-core and silver/dopamine-shell nanotags, Analytical and Bioanalytical Chemistry, 2018, 410, 2203–2210
5. Jiaxi Wang, Jie Li, Mingxia Gao*, Xiangmin Zhang, Self-assembling covalent organic framework functionalized magnetic graphene hydrophilic biocomposites as an ultrasensitive matrix for N-linked glycopeptide recognition, Nanoscale, 2017, 9, 10750–10756
6. Changlong Sun, Mingxia Gao*, Xiangmin Zhang, Surface-enhanced Raman scattering (SERS) imaging-guided real-time photothermal ablation of target cancer cells using polydopamine-encapsulated gold nanorods as multifunctional agents, Anal Bioanal Chem, 2017, 409:4915–4926
7. Peng Zhang, Xiaoni Fang, Guoquan Yan, Mingxia Gao*, Xiangmin Zhang, Highly efficient enrichment of low-abundance intact proteins by core-shell structured Fe3O4-chitosan@graphene composites, Talanta, 2017, 174,845–852
8. Yanan Wang, Jiaxi Wang, Mingxia Gao*, Xiangmin Zhang, Functional dual hydrophilic dendrimer-modified metal-organic framework for the selective enrichment of N-glycopeptides, Proteomics, 2017, 17(10), 1700005
9. Meng Chen, Ling Zhang, Mingxia Gao*, Xiangmin Zhang, High-sensitive bioorthogonal SERS tag for live cancer cell imaging by self-assembling core-satellites structure gold-silver nanocomposite, Talanta, 2017,172, 176–181
10. Yanan Wang, Jiaxi Wang, Mingxia Gao*, Xiangmin Zhang, A novel carbon material with nanopores prepared using a metal–organic framework as precursor for highly selective enrichment of N-linked glycans, Anal Bioanal Chem,2017, 49(2), 431-438
11. Jiaxi Wang, Jie Li, Yanan Wang, Mingxia Gao*, Xiangmin Zhang, Pengyuan Yang, Development of Versatile Metal−Organic Framework Functionalized Magnetic Graphene Core−Shell Biocomposite for Highly Specific Recognition of Glycopeptides, ACS Appl. Mater. Interfaces 2016, 8, 27482-27489.
12. Ling Zhang, Ren Zhang, Mingxia Gao*, Xiangmin Zhang*, Facile synthesis of thiol and alkynyl contained SERS reporter molecular and its usage in assembly of polydopamine protected bioorthogonal SERS tag for live cell imaging. Talanta, 2016,158, 315-321.
13. Peiming Zhang, Yong Zhang, Mingxia Gao*, XiangminZhang, Dendrimer-assisted hydrophilic magnetic nanoparticles as sensitive substrates for rapid recognition and enhanced isolation of target tumor cells, Talanta, 2016, 161, 925-931
14. Peiming Zhang, Mingxia Gao* , XiangminZhang, Functional dendrimer modified ultra-hydrophilic trapping copolymer network towards highly efficient cell capture, Talanta, 2016,153, 366–371
15. Zhi Huang, Guoquan Yan, Mingxia Gao*, and Xiangmin Zhang*, Array-Based Online Two Dimensional Liquid Chromatography System Applied to Effective Depletion of High-Abundance Proteins in Human Plasma, Anal. Chem. 2016, 88, 2440-2445
16. Jiaxi Wang, Yanan Wang, Mingxia Gao*, Xiangmin Zhang, Pengyuan Yang, Versatile metal-organic framework- functionalized magnetic grapheme nanoporous composites: as deft matrix for high-effective extraction and purification of the N-linked glycans, Analytica Chimica Acta 2016, 932 41-48.
17. Jiaxi Wang, Jie Li, Mingxia Gao*, Xiangmin Zhang, Chunhui Deng, A novel double-component MOAC honeycomb composite with pollen grains as a template for phosphoproteomics research, Talanta, 2016, 154,141-149
18. Jiaxi Wang, Yanan Wang, Mingxia Gao*, Xiangmin Zhang, Pengyuan Yang, Facile synthesis of hydrophilic polyamidoxime polymers as a novel solid-phase extraction matrix for sequential characterization of glycol and phosphoproteomes, Analytica Chimica Acta 2016,907, 69-76.
19. Yanan Wang, Jiaxi Wang, Mingxia Gao*, Xiangmin Zhang*, An Ultra Hydrophilic Dendrimer-Modified Magnetic Graphene with a Polydopamine Coating for Selective Enrichment of Glycopeptides, Journal of Materials Chemistry B, 2015, 3, 8711-8716
20. Jiaxi Wang, Yanan Wang, Mingxia Gao*, Xiangmin Zhang*, Pengyuan Yang, Multilayer Hydrophilic Poly(phenol-formaldehyde resin)-Coated Magnetic Graphene for Boronic Acid Immobilization as a Novel Matrix for Glycoproteome Analysis, ACS Appl. Mater. Interfaces 2015, 7, 16011−1601
21. Jiaxi Wang, Guoquan Yan, Mingxia Gao*, Xiangmin Zhang*, An effective and in-situ method based tresyl-functionalized porous polymer material for enrichment and digestion of membrane proteins and its application in extraction tips, Analytica Chimica Acta , 2015, 880, 77–83
22. Changlong Sun, Ling Zhang, Ren Zhang, Mingxia Gao*, Xiangmin Zhang*, Facilely synthesized polydopamine encapsulated surface-enhanced Raman scattering (SERS) probes for multiplex tumor associated cell surface antigen detection using SERS imaging, RSC Adv., 2015, 5, 72369–72372
23. Changlong Sun, Ren Zhang, Mingxia Gao*, Xiangmin Zhang, A Rapid and Simple Method for Efficient Capture and Accurate Discrimination of Circulating Tumor Cells Using Aptamer Conjugated Magnetic Beads and Surface-Enhanced Raman Scattering Imaging, Analytical and Bioanalytical Chemistry, 2015, 407, 8883–8892

近五年负责的项目  

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主持国家自然科学基金三项,其中面上2项

作为学术骨干参与国家重点基础研究发展计划三项,即973项目(项目号2007CB914100/3,多维、多模式、阵列式的蛋白质高效分离新技术的研究)。作为学术骨干参与国家重大科学研究计划 973课题(项目号KGH1615071,蛋白质定量新方法及相技术研究)一项,国家重点研发计划(蛋白质复合物的规模化分析鉴定方法 2016YFA0501401)是复旦大学唯一参加人员,学术骨干中排名第一。

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发表专利

 

已经授权专利五项

(授权号:ZL 2013 1 0137712.3;ZL 200910047016.7;:ZL 2013 1 0137689.8;ZL 2014 1 0320891.9;ZL 2014 1 0320892.3)

 
 

 

 

 

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更新时间  2021年4月8日 星期四 13:59